Biopolymers, and in particular chitosan, have great potential for biomedical applications. Chitosan is one of the most common polysaccharides in nature. It is found throughout much of the sea wildlife, especially in crustacean shells, and also in some fungal species.
Hydrogels are polymer-based materials with very high water content. Due to their similarity to extracellular matrix, they find many uses in regenerative medicine and other biomedical applications.
Chitosan is a unique natural polysaccharide due to its cationic nature, which confers many of its properties such as bioadhesion.
The research department has been tasking itself to create an extensive platform of multifunctional biopolymers, at the center of which are chitosan derivatives. These chemical modifications impart functional properties which the company is eagerly looking to leverage for a range of applications in tissue engineering and drug delivery.
Highly injectable gels suitable for a wide range of mechanical environments
Uniquely tailored properties for delivery of specific drug payloads
Perfectly control gelation by exposure to light
Cell-laden materials to print the constructs of the future, from organ replacements to organ-on-a-chip
We believe that with the right touch, we can add much value to the materials that nature has created.
Chenite, A. (2001). Rheological characterisation of thermogelling chitosan/glycerol-phosphate solutions. Carbohydrate Polymers, 46(1), 39-47. doi: 10.1016/s0144-8617(00)00281-2
Chenite, A., Chaput, C., Wang, D., Combes, C., Buschmann, M., & Hoemann, C. et al. (2000). Novel injectable neutral solutions of chitosan form biodegradable gels in situ. Biomaterials, 21(21), 2155-2161. doi: 10.1016/s0142-9612(00)00116-2
Ruel-Gariépy, E., Chenite, A., Chaput, C., Guirguis, S., & Leroux, J. (2000). Characterization of thermosensitive chitosan gels for the sustained delivery of drugs. International Journal Of Pharmaceutics, 203(1-2), 89-98. doi: 10.1016/s0378-5173(00)00428-2